What should be done before conducting wipe sampling to ensure safety?

Before conducting wipe sampling, it is essential to ensure that gloves are worn to protect both the sampler and the sample from contamination. Gloves act as a barrier, preventing skin contact with potentially hazardous substances that may be present on surfaces. They help maintain the integrity of the sample by avoiding the introduction of contaminants from the hands and ensuring that any hazardous materials do not come into contact with the skin. This is a fundamental practice in occupational hygiene that promotes safety and accuracy in sampling results.

The other options do not align with standard safety protocols. Removing all personal protective equipment would compromise safety, while the spaciousness of the area being sampled does not directly impact safety in terms of wipe sampling. Even though informing building occupants is a good practice for awareness and minimizing disruption, it is not a direct safety measure like wearing gloves, which directly protects against contamination and exposure.